Current classification of pulmonary hypertension

The classification of pulmonary hypertension (PH) has gone through several changes since the first classification proposed in 1973 at the International Conference on Primary Pulmonary Hypertension (PPH) in Geneva (Switzerland). Anyway, symposia always trended to create categories of PH based on similarities in pathophysiological mechanisms, clinical manifestation and therapeutic approaches. In addition to providing the best care of patients with this condition, the advantage of “clinical classification” relays on allowing the design of clinical trials in a well-defined group of patients with a shared underlying pathogenesis with the approval of 8 different drugs at all the world for the treatment of pulmonary arterial hypertension (PAH).
Within the 4th World Symposium on PH held in 2008, at Dana Point, California (USA), classifications were slightly modified to reflect accurately the information published in the last 5 years, as well as to clarify some areas. Changes approved at this meeting, mainly concern the Group 1, PAH.

Keywords: Pulmonary hypertension; Classification; Dana Point 2008